Among the famous whose DNA has been tested is Marie Antoinette, who belonged to maternal Haplogroup H (along with about half of all Europeans). Subsequent testing in 2012 on amummifiedhead, purportedly that of KingHenri IV of France, revealed that typing of a limited number of Y-STR's showed a Y-Dna haplogroup of G2a. Niall belongs toHaplogroup R1b1c7(M222). [75]Somerled belongs tohaplogroup R1a1. [42], United States presidentsJohn Adamsand his sonJohn Quincy Adamsbelonged to Y-DNA haplogroupR1b. It has been linked to maternally inherited thinness (Parker 2005), thinness at birth (Soini 2012), an increased body mass index (Liou 2007), and increased frequency of type 2 diabetes in the UK (Poulton 2002) and in Asia (Weng 2005 and Park 2008). Its very recent spread corresponds with the rise to power of theQing dynasty. Taking into consideration that the partial Y-chromosome profile is extremely rare in modern human databases, we concluded that both males could be paternally related." Haplogroup W was only identified in three individuals from the Kowalewko site. [44][45]The Takamuko clan of Japan claims agnatic descent fromCao Pi, who was the first Emperor of the state ofCao Weiand the eldest son ofCao Cao. 3. The development of the Neolithic lifestyle in the Fertile Crescent was about to bring a wave of Near Eastern immigrants that would change dramatically the genetic landscape of Europe. [5], In 1995 the body of Jesse James was exhumed and his DNA compared to that of two known living relatives; he was matched with each[according to whom?]. [15] It appears to occur fairly evenly across Europe at slightly lower levels than its parent. For people who have tested and are assigned the maternal haplogroup H5 or who are believed to have had that maternal haplogroup based on descendants tested. And at present it seems that only H5 indubitably came with early farmers from the Fertile Crescent. H15: found in Scotland, Germany, Poland, Austria, northern Italy, Central Asia (Turkmenistan), Iran and northern India. [9] In very large sample of the population of the Austrian Tyrol, H5a1 was found in 2%, whereas H5a was found at 2.9%. It should be noted that Dr. Moore's results examined some different parts of DNA (loci) from the result given here. Zhu Xi, the most influentialNeo-Confucianscholar and philosopher in Chinese history, may have belonged to Y-DNA haplogroupO2a1aaccording to the DNA test of one documented descendant. [25][26], The Y haplogroup of Richard III, last king of the House of York and last of the House of Plantagenet, was identified as Y-DNA G-P287, in contrast to the Y haplotypes of the putative modern relatives. Emanuel Swedenborg (16881772), the 18th century scientist and mystic from Sweden likely belonged to the haplogroup I1-BY229,[68] a haplogroup with a common ancestor about 1500 years ago who lived somewhere in central Scandinavia.[69]. The follow up study found that haplogroup H was strongly associated with increased lipoatrophy following a antiretroviral therapy. [88][89], Eddie Izzardbelongs to haplogroupI-M223according to the documentary seriesMeet the Izzards. The DNA results also disproved a branch that was later added to the family book. 2. Maybe Not", Bure DNA - DNA-research of the medieval Bure family in Sweden, "Ancient DNA of Emperor CAO Cao's granduncle matches those of his present descendants: a commentary on present Y chromosomes reveal the ancestry of Emperor CAO Cao of 1800 years ago", "Ancient DNA supports Emperor Cao's paternal genetic lineage belonging to haplogroup O2", "G2b-M377 / L72 / L183 / M283 Y Haplogroup Project (formerly G2c) Y-DNA SNP", "DNA Analysis of 5 People Who Helped Create America", "Whole-sequence analysis indicates that the Y chromosome C2*-Star Cluster traces back to ordinary Mongols, rather than Genghis Khan", "The Y-chromosome C3* star-cluster attributed to Genghis Khan's descendants is present at high frequency in the Kerey clan from Kazakhstan", "Molecular Genealogy of a Mongol Queen's Family and Her Possible Kinship with Genghis Khan", "Hitler was verwant met Somalirs, Berbers en Joden. "[12] However such a scenario would be too early for the date of c. 5500 BC. (8.5%)[citation needed], Mitochondria are key regulators of cell survival and death. 1960), a Turkish-American cardiothoracic surgeon, author, and television personality hosting the The Dr. Oz Show, belongs to haplogroup H2a1 according to the PBS TV series Faces of America. Toni de-Dios et al. [28], Yuya was Tutankhamun's great grandfather. To further confirm the identity, the tsar's brother, Grand Duke George, was exhumed and found to have the same mitochondrial heteroplasmy. Haplogroup H2b, H6a1b, H13a1a1a and many other undetermined H subclades (including many probable H1 and H5) turned up among the mtDNA samples from the Yamna culture, which occupied the Pontic-Caspian Steppe during the Early Bronze Age. H13 is also relatively common (2 to 8%) all the way from the Levant to Iberia, but rare in northern Europe. Chinese warlordCao Cao, who was posthumously titled Emperor Wu of the state ofCao Wei, apparently belonged to Y-DNA haplogroupO2according to DNA tests of some documented descendants. 4. In Europe estimated levels vary from a total absence in Volga-Uralic Finno-Ugrians to 8% in Slovaks and French. The test result supports genealogical information recorded in about 1610 by Johannes Bureus. Mulders contradicted interpretations of his research by some media outlets, which claimed that Hitler definitely had Jewish ancestry. Dr. Mehmet Oz (b. Genealogies show thatCharles II of Englandhad the same matrilineal ancestress as Queen Victoria, an unknown mistress ofTheobald I of Navarre. It is noteworthy though that the I2a men belonged exclusively to H1 and H3, a potent, albeit not conclusive evidence that H1 and H3 were lineages that belonged to Mesolithic hunter-gatherers from south-west Europe. The Cambridge Reference Sequence (CRS), the human mitochondrial sequence to which all other sequences are compared, belongs to haplogroup H. About one half of Europeans are of mt-DNA haplogroup H. Some H subclades are rare in Europe and geographically confined mostly to the Middle East. [4] It appears to be most frequent and diverse in the Western Caucasus, so an origin there has been suggested, while its subclade H5a appears European. This is a list of haplogroups of historic people.Haplogroups can be determined from the remains of historical figures, or derived from genealogical DNA tests of people who trace their direct maternal or paternal ancestry to a noted historical figure. H15a: found mostly in northwestern Europe / found in the Eneolithic Caucasus (Shulaveri-Shomu culture), in Bronze Age Russia (Fatyanovo culture) and in EBA Scotland, H16: found primarily in Germanic countries and Poland, but also in India / found in the Neolithic Rssen culutre in Germany, H16a: found in England, Germany and Poland, H16b: found mostly in Germanic countries and Poland, H17a: found in Sweden, Finland, Lithuania and Germany / found in Bell Beaker Czechia, H18: found in Portugal, France, England, Germany, Norway, Italy, Turkey and the Arabian peninsula, H20: found in England, Hungary, Italy, around the Near East and the Caucasus / found in Neolithic Catalonia, H23: found in the British Isles, Scandinavia, the Netherlands, Germany, the Czech Republic, Poland and Russia / found in the Neolithic LBK culutre in Germany, H24: found in Britain, Ireland, Spain, Germany, the Czech Republic, Poland, Denmark and Finland / found in the Funnelbeaker culutre in Sweden, H26a: found in Ireland, Scandinavia, Germany, the Czech Republic, Croatia and Serbia, H26b: found in Turkey / found in the Neolithic LBKT culutre in Hungary, H26c: found in Germany, Romania and Russia (Karelia), H27: found in central and northern Europe, but also in Central Asia (Turkmenistan), H27a: found in Ireland, northern Germany, Sweden, Finland and northern Russia, H28a: found especially in Finland, but also in Ukraine, Lithuania, Sweden, Germany and France / found in Bronze Age Latvia, H29: found in England, Germany, central Italy, Syria (Druzes) and Iran, H30: found in Italy, central Europe, Norway and the British Isles / found in the Neolithic LBK culutre in Germany, H31: found in especially in Scandinavia and Scotland, but also in England, Poland and Italy, H33: found in England, Germany, Italy, Greece and Lebanon, H39: found in Ireland, Britain and Norway / found in the early Neolithic Sopot culutre in Hungary, H40; found in Portugal, Germany and Poland / found in Bell Beaker Poland and in BA Israel, H41: found in Britain, northern France, Germany, Sweden, Poland and Romania / found in Bronze Age Russia (Fatyanovo culture) and in Hellenistic Lebanon, H44: found in Ireland, England, northern France, Ukraine and Bulgaria, H46: found in Ireland and Germany / found in the Early Neolithic Germany (LBK) and in Bell Beaker Germany. Language links are at the top of the page across from the title. In 2020, a genetic study showed that the figure of the French Revolution Jean-Paul Marat killed in 1793, had the haplogroup H2 (mtDNA). Both being matrilineal descendants of Queen Victoria, they shared the same haplogroup H. The mutations reported were 263G, 16111T and 16357C (an unknown subclade of H). The highest risk is found in the defining mutation of haplogroup H5a (T4336C), which has been associated with late onset AD by Santoro et al. The Corded Ware culture, which is associated with the expansion of Y-haplogroup R1a from the steppes to Central Europe and Scandinavia, yielded samples belonging to H1ca1, H2a1, H4a1, H5a1, H6a1a and H10e. There are many more recent branches below that. [91], Dr. Mehmet Ozbelongs to Y-DNA haplogroupJ2a1b. His two wives were all princesses of Yuan Dynasty. [6] H5a has been found in a Tagar (800 BC100 AD) man on the Russian steppe whose Y-DNA was R1a1a [13] and in Margrethe, 11th century AD Queen of Denmark. Alexander Hamiltonbelonged to Y-DNAhaplogroup I1. The results forY-DNAgenealogical DNA testsare either from the men themselves, or from men who have inferred paternal descent from historical figures. (2014) analysed the mtDNA of 395 elite Polish athletes (213 endurance athletes and 182 power athletes) and 413 sedentary controls and found that haplogroup H is among the most overrepresented mtDNA types among endurance athletes at the Olympic/World Class level. On 4 February 2013, University of Leicester researchers announced that there was an mtDNA match between that of a skeleton exhumed in Leicester suspected of belonging to Richard III and that of Joy Ibsen's son, Michael Ibsen, and a second unnamed direct maternal line descendant. Haplogroups can be determined from the remains of historical figures, or derived from genealogical DNA tests of people who trace their direct maternal or paternal ancestry to a noted historical figure. [4] However this risk is mitigated between subclades. With a Y-chromosome database containing close to 200,000 samples from different populations, Family Tree DNAs Chief Y-DNA Scientist, Professor Michael Hammer said that "scientific studies as well as records from our own database make it clear that one cannot reach the kind of conclusion featured in the published articles." Others may have come from the North Caucasus, like H2a1, or from the advance of Neolithic farmers from the Balkans to Northeast Europe, like H7. The personal genomics company 23andMe revealed that the mitochondrial haplogroup of business magnate and multi-billionaire Warren Buffett (born 1930) is H4a. Goats and sheep were the first animals domesticated, in the Taurus and Zagros mountains some 11,000 years ago. The highest frequencies of H1 are observed in the Iberian peninsula, south-west France and Sardinia. An extended 17-marker haplotype was published in 2007,[57] and the company Family Tree DNA has also published results for other markers in its standard first 12-marker panel. William was a direct descendant of John Hollister, an early colonist who immigrated to New England in 1612. [18], Leo Tolstoy, theRussianwriter, belonged toHaplogroup I1. The lowest frequencies are observed in Cyprus (31%), Finland (36%), Iceland (38%) as well as Belarus, Ukraine, Romania and Hungary (all 39%). The paternalgenomeof her father's line is HaplogroupR1b(Y-DNA). [84], Wyatt Emory CooperandAnderson Cooperbelong to Y-DNAhaplogroup R1a. Distribution of mtDNA haplogroup H5 in Europe, North Africa and the Middle East. The remainder belong toHaplogroup R1a (Y-DNA)below, and so have been suggested to be of Slavic origin. The supposed remains ofFrancesco Petrarcawere tested for DNA in 2003.[1]. The common C150T mutation has been found at strikingly higher frequency among Chinese and Italian centenarians and may be advantageous for longevity and resistance to stress according to Chen et al. human mitochondrial DNA (mtDNA) haplogroup, "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock", "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation", "The mtDNA and its role in Ancestry: Part XI (mtDNA Haplogroup H)", "Correcting for purifying selection: an improved human mitochondrial molecular clock", "High-resolution mtDNA evidence for the late-glacial resettlement of Europe from an Iberian refugium", "Timing and deciphering mitochondrial DNA macro-haplogroup R0 variability in Central Europe and Middle East", "May 'mitochondrial eve' and mitochondrial haplogroups play a role in neurodegeneration and Alzheimer's disease? [83]However, they are not closely related. Doras Folger, one of Benjamin Franklin's mother's six sisters, passed on her mtDNA to her 9th-great-granddaughter, Charlene Chambers King, therefore showing Franklin to belong to haplogroup V. mtDNA Haplogroup H(16111T, 16357C, 263G, 315.1C): Empress Alexandra of Russia's identity was confirmed by matching her mtDNA with that of her grand-nephew,Prince Philip, Duke of Edinburgh. It also allowed to validate the remains of Alexei, son of Nicholas II. MtDNA results indicate direct maternal descent while Y-DNA results indicate direct paternal descent; these are only two of many lines of descent. Other frequent hgs in the ME population were K, J and X, each occurring in two specimens. (2005) found that members of haplogroup H had increased chance of survival from severe sepsis at 180 days compared with individuals from other haplogroups. He is paternally descended from the Uldeme people of Cameroon. The male lineage of the medieval Bure kinship from Sweden has been identified as Y-DNA haplogroup G2a, based on several BigY tests carried out in 2014 on people living today. According to Family Tree DNA,[51]Genghis Khan is believed to have belonged toHaplogroup C-M217. Roostalu et al. Kevin, your maternal haplogroup is H5a1. Many answers came from the several ancient DNA studies conducted in 2015. [64][65], Emperor Higashiyama (1675-1710) belonged to Y-DNA haplogroup D1a2a1a2 (D-IMS-JST055457/CTS107), which is a subclade of haplogroup D1a2a which is prominent among the Jmon people that make up about 30% of modern Japanese ancestry. [39]The sample is most consistent withG2a3b1asamples and contains unusually high, rare values for markers DYS385B and DYS458 in this haplogroup G subgroup. The domestication of wild cereals could have taken place as early as 23,000 years before present in the southern Levant, although the actual cultivation of wheat and barley didn't start until 11,500 ybp. Megalithic people would have belonged essentially to Y-haplogroups I2, G2a and E1b1b, with the possible addition of J2 lineages during the Chalcolithic. It has long been known that mtDNA haplogroup H dominated the lines of Europe's aristocracies, while Y chromosomal R1b was the most common male lineage. (1994) tested the presumptive mitochondrial DNA of Tsaritsa Alexandra Fyodorovna of Russia and compared it to that of Prince Philip, Duke of Edinburgh. [66] Somerled belongs to haplogroup R1a1. Korguz (Chinese: ) was the son of a princess of Kublai Khan and he was the king of the Ongud and a descendant of Gok-Turk. There are also male and female haplogroups, so you can see where your male and female sides of the family originated back in pre-historic times. 1946), who won an Academy Award for Best Actress for her performance in the 1995 film Dead Man Walking, is a member of haplogroup H according to the BBC programme 'Coming Home' about her father's Welsh ancestry. In human mitochondrial genetics, Haplogroup H5 is a human mitochondrial DNA (mtDNA) haplogroup descended from Haplogroup H (mtDNA). The most recent report about a possible link between Alzheimer's disease (AD) and mtDNA genotypes might show evidence for subhaplogroup H5 as a risk factor for late onset AD.[11]. It was found in four individuals of from the Pre-Pottery Neolithic B site of Tell Halula in Syria, dating from circa 6800 BCE. H5* is present at low levels (1%3%) throughout the Near East. Haplogroup (hg) H was also the most frequent hg among the ME samples (40% of all analyzed ME individuals) . Based on the unverified images, iGENEA claimed that Tutankhamun belonged to Y-DNA haplogroup R1b1a2,[30][31] a claim that was rejected as "unscientific" by members of the team that had actually analysed the Eighteenth Dynasty mummies. In addition to the ubiquitous H5, these included H1, H2, H3, H7, H10, H11a, H16, H20 and H89. Tutankhamun's Y-DNA haplogroup was not published in the academic paper. Hofmanov et al. Famous Members. [33] In YFull's YTree a more detailed position is given for his Y-DNA under I-Y3120's subclades Y4460 > Y3106 > Y91535.[34]. H3: found throughout Europe and in the Maghreb / found in Neolithic Portugal, Spain, France, Germany and Scotland, in Bell Beaker Czechia and in MBA Scotland, H3b: found in the British Isles and Catalonia, H3c: found in Western Europe, including among the Basques / found in Neolithic France, H3k: found in the British Isles and northern Spain, H3v: found especially in Germanic countries, H4: found especially in central and western Europe, but also in the Near East and Caucasus, H4a: found in the Neolithic Cardium Pottery culture in Portugal and Spain, in Neolithic Scotland and southern France, in Bell Beaker Czechia and England, in EBA Czechia, and in Bronze Age Bulgaria and Latvia, H5: found throughout the Near East and Europe / found in almost all Neolithic cultures in Anatolia and Europe, H5a: found in the Cucuteni-Trypillian culture, H5a1: found in most of Europe and Siberia / found in Bell Beaker Netherlands, in Bronze Age Bulgaria, in the Tagar culture (Bronze Age Siberia), and in LBA Scotland, H5b2: found in north-west Europe / found in Bronze Age Russia (Fatyanovo culture), H5c: found in England, Germany, Poland, Ukraine / found in EBA England and MBA Wales, H5e: found in England, Germany, Serbia, Russia, H6: found throughout Europe, in the Near East and Central Asia, H6a1a: found in Bell Beaker Netherlands, in Bronze Age Russia (Fatyanovo culture) and in the Hallstatt culture, H6a1b: found in Bell Beaker England and Czechia, in MBA Scotland and in Iron Age Tian Shan, H7: found mostly in the Near East, Caucasus, Iran, Central Asia and Balto-Slavic countries / found in Bronze Age Poland, H7a : found in Chalcolithic Poland (Corded Ware culture) and in Bronze Age Bulgaria, H7d: found in the Neolithic Baalberge culutre in Germany, H8a: found in the Caucasus (Armenia), Syria, Anatolia and Greece, H8c: found in central and western Europe, Central Asia and the Altai, H10: found throughout Europe / found in Neolithic Germany, France and Portugal, H11a: found across most of northern, central and eastern Europe and in Central Asia / found in Mesolithic Lithuania, Middle Neolithic Germany, Megalithic Spain and among Iron Age Latins, H11b: found in Poland, Slovakia, Serbia and England / found in Bronze Age Poland, H13: found mostly around the Caucasus, Iran, Anatolia, and Sardinia, but also across along the Mediterranean coasts of Europe, H13a2: found among the ancient Caucasian Alans and Tian Shan Huns, H14: found mostly in the Near East and Caucasus, H14a: found mostly in the Levant, Kurdistan, Iran, but also in Bulgaria, Greece, Italy, the Czech Republic, Scotland and Ireland / found in Sumerian Syria and in Hellenistic Lebanon, H14b: found in Iran, Turkey, Germany and France. Click on Preferences. [16] Another analysis revealed that purported skull of Petrarca belonged to a woman, the DNA from rib belonged to mtDNA haplogroup J2. Several scientists have created their own theories about the Y-chromosomal haplogroup (and therefore the patrilineal ancestry) of Genghis Khan. In 2019, Leonard Sax published an article titled "Aus den Gemeinden von Burgenland: Revisiting the question of Adolf Hitlers paternal grandfather". R-Z159 Z159 * Z350 * Z160 +2 SNPs formed 3900 ybp, TMRCA 3500 ybp info. Fred Phelps, the creator of the infamous Westboro Baptist Church, belongs tohaplogroup R1b. [90], Matt Lauerbelongs to Y-DNA haplogroupJ2. [48], Toghan, Genghis Khan's sixth son has claimed descendants who have Y haplogroup C2b1a1b1-F1756 just like the first son of Genesis Khan, Jochi's descendants in the Kazakh Tore clan. William Welles Hollister, a famous Californian rancher, belonged to Y-DNAhaplogroup R1a1. When the climate started warming up and the ice caps progressively receded, people recolonised Europe from these LGM refugia. Nelson Mandela, former President of South Africa, belongs to mtDNA haplogroup L0d (previously known as L1d), a subgroup ofHaplogroup L0 (mtDNA).[22][23][24][25]. In 2004 British historian John Ashdown-Hill traced a British-born woman living in Canada, Joy Ibsen (ne Brown), who is a direct maternal line descendant of Anne of York, Duchess of Exeter, a sister of Richard III of England. The Ongud claimed descent from the Shatuo, prominent in the era of the Five Dynasties and Ten Kingdoms period. Eddie Izzard belongs to haplogroup I-M223 according to the documentary series Meet the Izzards. [27], In order to verify whether the body of a woman entombed near Sweyn II of Denmark in Roskilde Cathedral is that of his mother Estrid, mtDNA from pulp of teeth from each of the two bodies was extracted and analysed. [63]Combining these sources gives the consolidated 21-marker haplotype below. Found among the Angles and Lombards. Here is a summary of all European kings and queens (and crown princes) whose haplogroup can be deduced from the testing of a relative. Analysis of a handkerchief with blood traces said to have been obtained at the execution of Louis XVI of France, suggested that he may have belonged to Y-DNA haplogroup G-M201. The most principal occupant, Gaodang King Korguz, had mtDNA of haplogroup D4m2. Language links are at the top of the page across from the title. (2015) tested five more Neolithic farmers from the same period, two from the same site in Turkey and three from Greece, but none belonged to H. Szcsnyi-Nagy et al. Rurik, whose male-line descendants foundedKievan Rus', and ultimately theTsardom of RussiaincludingIvan the Terribleuntil 1598, belonged to theUralo-FinnicY-DNAHaplogroup N(N1c1). This suggests that the Takamuko clan also belongs to Y-DNA haplogroupO2. I found this to be one of the coolest parts of my 23andMe results. Comparison of overall haplogroup distribution (R C test of independence) revealed significant differences among the three Jewish populations (RU, Poland and Romania, P=0.017).Using an unplanned . [69][70], Fath Ali Shah Qajar (1772-1834), the second emperor/shah of the Qajar Dynasty of Persia belonged to haplogroup J1 with DYS388 = 13 as deducted from testing of descendants of several of his sons.[71]. Catherine the Great is 11-knee relation of Queen Victoria on this lineage. Predicted Y-DNA haplogroup G2a, based on ancient Y-STR profiles. According to the authors of the study, "Probably Napolon also knew his remote oriental patrilineal origins, because Francesco Buonaparte (the Giovanni son), who was a mercenary under the orders of the Genoa Republic in Ajaccio in 1490, was nicknamed The Maur of Sarzane ". calculated by Lusa Pereira, Martin Richards, Ana Goios, et al. The modern distributions of H1 and H3 support a Late Glacial recolonisation of Western and Central Europe from the Franco-Cantabrian refugium. NOTE BY JAN A JONES: Source in respect of date of birth and date of death: HENRY JONES JNR FAMILY BIBLE (1872). His Y-DNA Haplogroup was I1a. It can also be said that this result is German-specific, so Paul I was most likely the real son of his official father Peter III, and not the son of a lover, as was speculated. The mutation defining haplogroup H took place at least 25,000 years ago, and perhaps closer to 30,000 years ago. Its highest frequencies are observed in Wales (8.5%), Slovenia (8%), Latvia (7%), Belgium (7%), Romania (6%), Bosnia-Herzegovina (5.5%), Russia (5%), Germany (5%), Slovakia (5%), Switzerland (4.5%) and Poland (4.5%). These Neolithic farmers potentially belonged to haplogroups H5, as well as J1c, K1a, N1a, T2 and X2, all of which have been found in ancient Neolithic samples from Europe and Anatolia, and are also found throughout the Middle East today. However, King et al. The Unetice culture, which is thought to mark the arrival of R1b in Central Europe (but overlapping with the previous R1a expansion), had individuals belonging to H2a1a3, H3, H4a1a1a2, H7h, H11a, H82a. In other words, these mutations are so unique that they could only come from other cells with the same mutations. Mulders commented: I never wrote that Hitler was a Jew, or that he had a Jewish grandfather. The Takamuko clan is most famous forTakamuko no Kuromaro. [citation needed]. [11][12], Empress Alexandra of Russia and her children, Olga, Tatiana, Maria, Anastasia, and Alexei were identified as belonging to mtDNA haplogroup H (16111T, 16357C, 263G, 315.1C).

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famous h5a1 haplogroup